Drawn traditionally and then colored in SAI
An attempt at making a Tyrant (More specifically one of the t-013 type Tyrants seen in Resident Evil: Damnation) infected with the Uroboros virus from RE5.
We never really saw the result of a perfect fusion with Uroboros, though one might suspect that it would have looked something like the Uroboros Mkono did prior to losing control (Humanoid with cat-like eyes similar to Wesker).
Now, according to the series only a select few of humans with special DNA are capable of becoming Tyrants (I'm pretty sure the rest become Zombies) the same was apparently true with the Uroboros adaption that only those who were "worthy" would evolve rather then lose control. Due to both being products of the Progenitor virus I believe there is a connection between the two (If a human is capable of becoming a Tyrant they possess the same DNA necessary to perfectly fuse with Uroboros). Unfortunately we'll probably never get a chance to see it..